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1. Introduction. The purpose of this review is to refine the neuroanatomical framework of the dopamine reward circuitry, in light of recent observations on drug-reward trigger zones using intracranial self-administration procedures in rats.

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Rutgers New Jersey Medical School: A unit of Rutgers Biomedical and Health Sciences, New Jersey Medical School is the oldest and largest school of allopathic medicine in New Jersey.

DOPAMINE AND GLUTAMATE IN psychiatric disorders dopamine AND GLUTAMATE IN PSYCHIATRIC DISORDERS Edited by WERNER J. SCHMIDT, PhD Department of Neuropharmacology

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Reward pathway in the brain | Processing the Environment | MCAT | Khan Academy These assays can thus be utilized as a method of screening for agents which can be utilized for the treatment of acute or chronic abuse and/or addiction to stimulants, or a behavioral disorder, which results in enhanced dopamine levels or surges in dopamine levels in the brain of a patient.

Methamphetamine (MP) is a widely abused psychostimulant. There are currently no fda approved pharmacotherapies for the MP addict. The antidepressant, mirtazapine (Mirt) is a high affinity antagonist at several monoaminergic receptors that are affected by MP.

1. INTRODUCTION. The purpose of this review is to refine the neuroanatomical framework of the dopamine reward circuitry, in light of recent observations on drug reward trigger zones using intracranial self-administration procedures in rats.

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