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Baclofen is commonly prescribed to treat symptoms associated with spinal cord disease or injury, but more recently has been tapped for off-label uses such as the management of alcohol, opioid, cocaine, and tobacco dependence 1,2.

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Previous research “showed good results for treating alcohol dependence with high-dose baclofen.” Early studies indicated positive results, leading many physicians to prescribe the drug. In France, baclofen has been widely used for alcohol dependence treatment since 2014.

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